TIBBIY IMPLANTLARDA KORROZIYA VA TRIBOKORROZIYA: BIOKOMPATIBILIK, YALLIG‘LANISH HAMDA KLINIK XAVFLARNI BOSHQARISH
Keywords:
tibbiy implant, korroziya, tribokorroziya, biokompatibilik, metall ionlariAbstract
Maqolada ortopedik, stomatologik va yurak-qon tomir implantlarida uchraydigan korroziya hamda tribokorroziya jarayonlari tibbiy-biologik nuqtai nazardan tahlil qilindi. Tadqiqot 2016–2025-yillarda e’lon qilingan birlamchi eksperimental, klinik va implant-retrieval tadqiqotlari, shuningdek ISO 10993-15:2019 standarti va FDA xavfsizlik ma’lumotlariga tayangan strukturaviy adabiyotlar tahlili shaklida bajarildi. Natijalar passiv oksid qatlamining xloridlar, past pH, ftoridlar, biofilm, mikroharakat va ishqalanish ta’sirida shikastlanishi metall ionlari hamda zarrachalar ajralishiga olib kelishini ko‘rsatdi. Ajralgan titan, kobalt, xrom, alyuminiy yoki vanadiy mahsulotlari oqsillar bilan kompleks hosil qilib, makrofag faollashuvi, oksidlovchi stress, sitokinlar ajralishi va peri-implant to‘qimalarda osteoliz xavfini oshirishi mumkin. Titan qotishmalari umumiy barqarorligi yuqori bo‘lsa-da, dental muhitda ftorid va kislotali pH, modulli ortopedik birikmalarda esa fretting-korroziya muhim cheklov bo‘lib qoladi. Maqolada material tanlash, galvanik juftliklarni cheklash, sirtni modifikatsiyalash va klinik monitoringni birlashtiruvchi boshqaruv modeli taklif etildi.
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